DeCS Server - List Exact Term

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DeCS

Descriptor English:

Pick Disease of the Brain

Descriptor Spanish:

Enfermedad de Pick

Descriptor Portuguese:

Doença de Pick

Synonyms English:

Circumscribed Lobar Atrophy of the Brain
Lobar Atrophy (Brain)

Tree Number:

Definition English:

A rare form of DEMENTIA that is sometimes familial. Clinical features include APHASIA; APRAXIA; CONFUSION; ANOMIA; memory loss; and personality deterioration. This pattern is consistent with the pathologic findings of circumscribed atrophy of the poles of the FRONTAL LOBE and TEMPORAL LOBE. Neuronal loss is maximal in the HIPPOCAMPUS, entorhinal cortex, and AMYGDALA. Some ballooned cortical neurons contain argentophylic (Pick) bodies. (From Brain Pathol 1998 Apr;8(2):339-54; Adams et al., Principles of Neurology, 6th ed, pp1057-9)

History Note English:

2000; for PICKS DISEASE OF BRAIN use DEMENTIA 1992-1999

Allowable Qualifiers English:

Record Number:

34272

Unique Identifier:

D020774

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